Adjacent to the existing Tisch Hospital, this new 5-story building houses an expanded and relocated Radiation Oncology Department on the second level, including a new linear accelerator, bracotherapy and tomagraphy treatment rooms with high-density concrete shielding. The remaining levels, including the roof, contain essential power systems for the entire NYU Langone Health campus. The third level contains backup emergency power systems, while the fourth level contains a cogeneration plant for creating additional energy. On the roof level, primary power systems distribute incoming power.

The Energy Building is constructed over the existing materials and waste loading dock through the use of transfer trusses at the 2nd Floor that are integrated into the Radiation Oncology spaces. The Ground Floor contains provisions for a future expansion of the Tisch Hospital kitchen. Built on a fast-track schedule, the Energy Building was designed to accommodate updated flood mitigation measures.